European Science Methodical Journal

SYNTHESIS AND CHARACTERIZATION OF HYDROXYAPATITE NANOPARTICLES FROM BOVINE BONE BY THERMAL HEAT TREATMENT AND EFFECTS ON MACROPHAGES AND TNFΑ IN MICE

Alyaa I. Aldebs

College of Pharmacy - Al-Qadisiyah University - Iraq

Ahmed M. H. Abudken

College of Pharmacy - Al-Qadisiyah University - Iraq

Hanaa. A. Abdulameer

College of Pharmacy - Al-Qadisiyah University - Iraq

Keywords: biomaterial, macrophages, calcination process, TNFα, Obese mice.

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Abstract

Due to the fact that its structure and function comparable to those of reel human bone hydroxyapatite (HA) is regarded as an essential bio-ceramic component that generated a wide range of applications in the field of biomaterials. Consequently, the primary purpose of this study to produce a pure nanoparticles powder of hydroxyapatite through calcination process while the bovine bone is subjected to heat treatment at 800℃.